IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 61 61 60
ANN 4.0 31 31 31
ARB 56 56 57
IEDB Consensus 36 36 36
NetMHCcons 80 80 80
NetMHCpan 2.8 69 69 69
NetMHCpan 3.0 61 63 60
NetMHCpan 4.0 BA 83 83 83
NetMHCpan 4.0 EL 21 20 21
NetMHCpan 4.1 BA 91 91 90
NetMHCpan 4.1 EL 50 50 50
PickPocket 63 63 63
SMM 40 39 41
SMMPMBEC 40 39 41
mhcflurry 1.2.0 51 51 51

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1036593   HLA-A*02:01   9   14   9   binary   0.425   0.756   0.388   0.733   0.499   0.800   0.463   0.778   0.499   0.800   0.573   0.844   0.462   0.778   0.499   0.800   0.425   0.756   0.499   0.800   0.499   0.800   0.592   0.856   0.426   0.756   0.425   0.756   0.203   0.622 
 1036593   HLA-A*03:01   10   11   7   binary   0.478   0.786   0.359   0.714   0.717   0.929   0.418   0.750   0.657   0.893   0.478   0.786   0.478   0.786   0.598   0.857   0.359   0.714   0.598   0.857   0.538   0.821   0.717   0.929   0.478   0.786   0.418   0.750   0.418   0.750 
 1036593   HLA-A*11:01   10   11   6   binary   0.693   0.900   0.635   0.867   0.693   0.900   0.635   0.867   0.751   0.933   0.751   0.933   0.751   0.933   0.751   0.933   0.462   0.767   0.751   0.933   0.577   0.833   0.577   0.833   0.608   0.867   0.635   0.867   0.693   0.900 
 1036593   HLA-B*07:02   9   19   9   binary   0.616   0.856   0.577   0.833   0.539   0.811   0.540   0.811   0.558   0.822   0.558   0.822   0.481   0.778   0.558   0.822   0.327   0.689   0.616   0.856   0.423   0.744   0.616   0.856   0.577   0.833   0.597   0.844   0.712   0.911 
 1036593   HLA-B*08:01   9   12   8   binary   0.666   0.906   0.563   0.844   0.256   0.656   0.513   0.812   0.717   0.938   0.615   0.875   0.768   0.969   0.768   0.969   0.666   0.906   0.768   0.969   0.717   0.938   0.256   0.656   0.410   0.750   0.512   0.812   0.666   0.906